WHY WE NEED CLINICAL TRIALS

  • The role of a clinical trial in improving cancer outcomes
  • What is a clinical trial?
  • What is the purpose of a clinical trial?

PARTICIPATING IN A CLINICAL TRIAL

  • Selecting the appropriate trial for a child
  • Is participation voluntary?

BENEFITS AND RISKS IN PARTICIPATING

  • The benefits of participating
  • Risks in participating
  • Risks in NOT participating

CREATING PEDIATRIC CLINICAL TRIALS

  • COG's role in creating pediatric clinical trials
  • Creating a network for effective clinical trials
  • COG's role in creating access to clinical trials
  • CHOC's involvement with COG

CLINICAL TRIALS AT CHOC:

TYPES OF TRIALS OFFERED AT CHOC

  • Trials available other than therapeutic
  • Trials for first-line therapy or for recurrent disease
  • Clinical trials for the AYA patient

THE DIFFERENT PHASES OF CLINICAL TRIALS

  • What is a Phase 1 clinical trial?
  • What is a Phase 2 clinical trial?
  • What is a Phase 3 clinical trial?

THE CLINICAL TRIALS TEAM:

THE PI OR PRINCIPAL INVESTIGATOR

  • The role of the PI in designing the study
  • The PI at CHOC

COORDINATION AND OVERSIGHT OF CLINICAL TRIALS

  • Responsibilities of the Clinical Research Coordinator
  • The role of the Institutional Review Board

STEPS IN THE CLINICAL TRIALS PROCESS:

IMPROVING TREATMENTS AND OUTCOMES

  • The Protocol
  • The Comprehensive Treatment Plan or “Roadmap”
  • The occurrence of an adverse event
  • The Consent Conference
  • The Informed Consent Form

LOOKING TO THE FUTURE:

THE HYUNDAI GENOMICS PROJECT

  • Participating in the Genomics Project
  • Why CHOC collects and stores tumor tissue
  • The CISCO Tumor Board at CHOC
  • A final word about clinical trials

CLINICAL TRIALS eBOOK

The eBook has further information and helpful links about clinical trials.

You can view it here, and/or submit your email address to receive a link to a PDF of the Clinical Trials eBook